Expression of LC3 alone failed to reach statistical significance in terms of association with EAC survival; however, patients with low levels of both LC3B and p62, an autophagy cargo-identifying protein, fared worse than those with high co-expression or ‘mixed’ type lesions (displaying high expression of LC3 and low expression of p62 or vice versa) [ 42 ].
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Roles for Autophagy in Esophageal Carcinogenesis: Implications for Improving Patient Outcomes.
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