Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein.

Analyses of individual anterograde and retrograde transport revealed that although expression of FLAG-KLC1S460D appeared to reduce APP-EGFP transport in both directions, these reductions did not reach statistical significance (Fig. 3 a).

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