In both experiments, at the early interval post infection, hTLR4/MD-2 mice had significantly more KC ( Figure 4a and b ) and nearly significant or significantly more G-CSF ( Figure 4c and d , respectively) in plasma than did wild type mice.
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Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during <i>Coxiella burnetii</i> infection.
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