TcellSubC: An Atlas of the Subcellular Proteome of Human T Cells.

Confirming the MS data, T cells had intracellular levels of C3, and confirming the translocation observed in the MS data, the quantitative data from the images of C3 staining showed slightly higher C3 abundance in the nucleus compared to the cytosol upon TCR stimulation which was clearly significant ( P < 0.001) ( Figure 2D ).

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cytoplasm was highly significant ( P < 0.001) in both CD3/28 and P/I stimulated cells as compared to unstimulated cells despite a general upregulation of NFATC2 especially upon TCR stimulation ( Figure 2C ).

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