Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis.

report genetic overlap with inflammatory bowel disease [IBD] by comparing the number of nominally significant single nucleotide polymorphisms [SNPs] in both phenotypes. 3 The most frequently cited environmental risk factors are medications, with non-steroidal anti-inflammatory drugs [NSAIDs], proton-pump inhibitors [PPIs] and selective serotonin reuptake inhibitors [SSRIs] most commonly implicated. 5–7 There have been no reported investigations of potential pharmacogenetic risk factors for microscopic colitis.

also in 7,732 other papers