Characterization of the 18 kDa translocator protein (TSPO) expression in post-mortem normal and Alzheimer's disease brains.

Brain Pathol · 2020 · PMC6904423 · PMID 31276244

Europe PMC DOI

hedged sentences

0.1250

closest p · 2.5× alpha

0.1250

boldest claim

The sentences

did not reach statistical significanceP = 0.1250not close (p > 0.1)

However, these regional differences did not reach statistical significance in either group (CTRL: P = 0.1250 and AD: P = 0.1310, Wilcoxon matched‐pairs signed‐rank test).

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marginally significantno p-value reported

AD subjects had a marginally significant higher TSPO‐ir burden in the cortex and a statistically significant higher TSPO‐ir burden in the white matter compared to CTRL subjects (cortex: Mann–Whitney U = 175.5, P = 0.0516; white matter: Mann–Whitney U = 161.5, P = 0.0235).

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