Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer.

Sci Rep · 2019 · PMC6904466 · PMID 31822727

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.1300

boldest claim

The sentences

highly significantp = 2 × 10 −5actually significant

Again, a highly significant (p = 2 × 10 −5 ) overlap was observed in kidney cancer.

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of borderline significancep = 0.07so close (0.05 < p ≤ 0.1)

24 sub-threshold RCC-susceptibility loci either overlapped or lay within 25 kb of a HIF-binding site, which was of borderline significance (p = 0.07) (Fig. 6C ).

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did not reach statistical significancep = 0.13not close (p > 0.1)

6B ) did not reach statistical significance (p = 0.13). 24 sub-threshold RCC-susceptibility loci either overlapped or lay within 25 kb of a HIF-binding site, which was of borderline significance (p = 0.07) (Fig. 6C ).

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