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Vaccination against the digestive enzyme Cathepsin B using a YS1646 Salmonella enterica Typhimurium vector provides almost complete protection against Schistosoma mansoni challenge in a mouse model.

PLoS Negl Trop Dis · 2019 · PMC6907844 · PMID 31790394

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The IM→PO group also had higher intestinal IgA titers than controls, but this increase did not reach statistical significance (259.8 ± 19.4 ng/g).

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