So next, we examined the protein expression of factors in the STING pathway and found no significant effect on STING protein, even if there was a clear trend for decreased STING protein for HIV/HSV, but the STING downstream factor TBK1 was significantly decreased and a there was a trend of decreased expression for IRF3 in the dual exposed DCs compared to HIV alone ( Figure 7C ).
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HSV-2 Cellular Programming Enables Productive HIV Infection in Dendritic Cells.
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