Effects of Mineralocorticoid Receptor Antagonists on Atrial Fibrillation Occurrence: A Systematic Review, Meta-Analysis, and Meta-Regression to Identify Modifying Factors.

J Am Heart Assoc · 2019 · PMC6915291 · PMID 31711383

Europe PMC DOI

hedged sentence

0.1100

closest p · 2.2× alpha

0.1100

boldest claim

The sentences

did not reach statistical significanceP =0.11not close (p > 0.1)

This may be explained by the antifibrotic effects of MRAs, since fibrosis is present in patients with AF to a greater extent compared with those without AF 34 Unfortunately, when restricting meta‐analysis only to RCT versus placebo subgroup, the efficacy of MRAs did not reach statistical significance (OR, 0.76; 95% CI, 0.55–1.06 [ P =0.11]).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.