High OX-40 expression in the tumor immune infiltrate is a favorable prognostic factor of overall survival in non-small cell lung cancer.

J Immunother Cancer · 2019 · PMC6915970 · PMID 31843013

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.0800

boldest claim

The sentences

highly significantp ≤ 0.01actually significant

When analyzing the correlation between OX-40 IHC levels and mRNA expression of immune-related genes, we found the following markers of immune inflammation to have a highly significant positive association ( p ≤ 0.01): CD3, CD8, IFN-gamma, ICOS, CXCL9, CXCL10, CCL5, and granzyme K (Fig. 3 ).

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did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

This favorable prognostic effect was seen in both adenocarcinoma and squamous cell carcinoma, though it did not reach statistical significance in the adenocarcinoma subgroup ( p = 0.08 and p = 0.04, respectively) (Additional file 1 : Figure S1).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.