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Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice.

Arthritis Res Ther · 2019 · PMC6918687 · PMID 31847895

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Furthermore, takinib-treated mice showed a trend toward reduced histological scores in pannus and bone resorption (~ 40% each) (Fig. 3 g, h).

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