Subcortical Ischemic Vascular Cognitive Impairment: Insights from Reaction Time Measures.

Although there was some evidence in support of this suggestion, namely that patients with moderate/severe levels of periventricular LA showed slower RT and higher IIV than those patients with mild levels for the DP task, these differences failed to reach statistical significance and, in response to the DA condition, performance was worse (but again not significantly so) for the mild subgroup.

also in 6,035 other papers

It is likely that the lack of significance is a result of the low numbers of participants in each of the SIVCI subgroups (mild n = 15, versus moderate/severe, n = 12); nevertheless, it is also possible that the level of CT- or MRI-visible periventricular white matter change alone does not fully explain the highly significant slowing and raised IIV in SIVCI compared to CH, which may be the result also of the impact of ‘silent’ white matter disease and/or other disease-related changes in SIVCI.

also in 132,142 other papers