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Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential.

Redox Biol · 2020 · PMC6921228 · PMID 31926622

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We found that KO iMEFs showed more PCx and less PDH activity than WT iMEFs, although differences did not reach statistical significance ( Fig. 6 E).

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