6 (B)) showed a trend of increase towards September of the first treatment year, but there was no significant difference in IL-4 or IL-5 secretion between placebo and BM32 treated groups at any of the time points analysed.
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Two years of treatment with the recombinant grass pollen allergy vaccine BM32 induces a continuously increasing allergen-specific IgG<sub>4</sub> response.
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