Barely Significant
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Two years of treatment with the recombinant grass pollen allergy vaccine BM32 induces a continuously increasing allergen-specific IgG<sub>4</sub> response.

EBioMedicine · 2019 · PMC6921329 · PMID 31786130

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showed a trendno p-value reported
6 (B)) showed a trend of increase towards September of the first treatment year, but there was no significant difference in IL-4 or IL-5 secretion between placebo and BM32 treated groups at any of the time points analysed.

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