A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.

Nat Cell Biol · 2019 · PMC6927814 · PMID 31685988

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did not reach statistical significanceno p-value reported

While corresponding Eif2b5 +/- mice show a further increase of MYC-positive cells, this did not reach statistical significance ( Fig. 6c,d and Extended Data 7d,e ).

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