A Phase II, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study Evaluating the Efficacy and Safety of Alpha-1 Antitrypsin (AAT) (Glassia<sup>®</sup>) in the Treatment of Recent-Onset Type 1 Diabetes.

Int J Mol Sci · 2019 · PMC6928874 · PMID 31795482

Europe PMC DOI

hedged sentences

0.0545

closest p · 1.1× alpha

0.0770

boldest claim

The sentences

borderline significancep = 0.0545so close (0.05 < p ≤ 0.1)

The effect of age ≥12 years had a borderline significance ( p = 0.0545).

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did not reach statistical significancep = 0.077so close (0.05 < p ≤ 0.1)

The difference within the 12–18-year subgroup, nonetheless, did not reach statistical significance ( p = 0.077, AAT-120 mg/kg vs. placebo). 2.4.

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