Downregulation of the endogenous SIX1 by shRNA in TPC-1 cells not only showed a trend of slowing down the tumor associated weight loss ( Figure 7A ), but also significantly reduced the volume as well as the weight of xenografted tumors ( Figures 7B–D ).
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SIX1 Activates STAT3 Signaling to Promote the Proliferation of Thyroid Carcinoma via EYA1.
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