Amyloid and tau imaging biomarkers explain cognitive decline from late middle-age.

Weakly significant differences in health characteristics were observed for waist-to-hip ratio (adjusted for sex) at the end of the study period ( P = 0.05; A+T− less than A−T−) and serum fasting insulin at the beginning of the study period ( P = 0.02; A−T+ > both A−T− and A+T−).

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