Transcriptional changes during hepatic ischemia-reperfusion in the rat.

PLoS One · 2019 · PMC6938360 · PMID 31891620

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did not reach statistical significanceno p-value reported

Activating phosphorylation sites on Jun (Y170) and Fos (T232) were increased in the reperfused lobe, but did not reach statistical significance.

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borderline significantno p-value reported

Canonical Pathway analyses comparing the reperfused or non-ischemic lobes to the pooled shams yielded no significant findings at 0.5 hr and only borderline significant changes at the 2 and 6 hr time points.

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highly significantno p-value reported

The most highly significant upstream regulators in the reperfused lobe (PDGF BB, IL1B, TNF, IGF1) were based on a relatively limited target gene set that included immediate early genes (ATF3, EGR1, FOS, JUN).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.