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H19 Increases IL-17A/IL-23 Releases via Regulating VDR by Interacting with miR675-5p/miR22-5p in Ankylosing Spondylitis.

Mol Ther Nucleic Acids · 2020 · PMC6938967 · PMID 31887550

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showed a trendno p-value reported
The luciferase activity of H19-WT and VDR-WT was suppressed by miR22-5p mimics ( Figures 6 A and 6B) and miR675-5p mimics ( Figures 6 C and 6D); and miR675-5p mimics showed a trend toward decreasing the luciferase activity of H19-MUT, indicating that the relationship between H19 and miR675-5p is diverse. 15 , 21 However, the luciferase activity of H19-MUT and VDR-MUT in cells transfected with the two miRNA mimics showed no statistical differences ( Figures 6 A–6D).

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