Farnesoid X Receptor Agonism, Acetyl-Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of <i>De Novo</i> Lipogenesis in a Murine NASH Model.

Hepatol Commun · 2020 · PMC6939503 · PMID 31909359

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a strong trendno p-value reported

The decrease in peripheral fat was present despite increased food intake after 6 weeks of LJP305 treatment and was associated with a strong trend of reduction in circulating leptin levels (35% vs. vehicle) (Fig. 5 F).

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