Single-nucleotide polymorphism of rs7944135 (macrophage-expressed gene 1) is associated with hepatitis B surface antigen seroclearance in chronic hepatitis B infection: A cohort study.

Medicine (Baltimore) · 2019 · PMC6940119 · PMID 31860948

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The cumulative fraction curve showed a trend of HBV carriers with the AA genotype of rs7944135 indicating higher susceptibility to HBsAg seroclearnce compared to those with the AG or GG genotype (Fig. 1 ). 3.5 Correlation between the MPEG1 rs7944135 genotype and days of HBV DNA undetectable We further investigated the correlation between the time taken to HBV DNA undetectable and MPEG1 gene rs7944135 genotypes: AA, AG, and GG.

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