Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression.

Redox Biol · 2020 · PMC6940621 · PMID 31901728

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Importantly, the levels of Pparg2 mRNA were found to be induced by HFD exposure in both genotypes, whereas the expression of Pparg2 showed a trend to be lower in Nrf2 (L)-KO mice compared to control mice ( Fig. 3 B).

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