An In Vitro Study on the Combination Effect of Metformin and N-Acetyl Cysteine against Hyperglycaemia-Induced Cardiac Damage.

Nutrients · 2019 · PMC6950330 · PMID 31766382

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closest p · 1.0× alpha

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showed a trendp < 0.05actually significant

Treatment with MET (1.39; p < 0.001) significantly prevented mitochondrial depolarisation, whereas NAC as well as the combination of MET+NAC only showed a trend towards decreased depolarisation ( p < 0.05, Figure 7 ). 3.8.

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an increasing trendno p-value reported

Interestingly, MET, NAC showed an increasing trend, whereas the combination (MET+NAC) treatment significantly ( p < 0.05) increased AKT expression ( Figure 11 C).

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