DNA hypermethylation associated with upregulated gene expression in prostate cancer demonstrates the diversity of epigenetic regulation.

BMC Med Genomics · 2020 · PMC6950795 · PMID 31914996

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a clear trendno p-value reported

Observing the top 10 genes from the canonical UPDOWN-only group, we spotted a clear trend; hypermethylated probes tend to form a cluster around the TSS of the associated genes, and this cluster usually overlaps with a CGI.

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