Effect of Genetic and Nongenetic Factors on the Clinical Response to Mineralocorticoid Receptor Antagonist Therapy in Egyptians with Heart Failure.

Clin Transl Sci · 2020 · PMC6951455 · PMID 31560448

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showed a trendno p-value reported

22 showed a trend toward greater diastolic blood pressure reduction with ACEI therapy in individuals with the rs2070950 GG genotype. 22 In a mixed US population treated with spironolactone for HF, we showed a greater K increase with the NR3C2 rs2070951G allele, 23 which has been associated with mineralocorticoid rec

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