Early-life blockade of NMDA receptors induces epigenetic abnormalities in the adult medial prefrontal cortex: possible involvement in memory impairment in trace fear conditioning.

Psychopharmacology (Berl) · 2020 · PMC6952333 · PMID 31654083

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

did not reach statistical significancep = 0.053so close (0.05 < p ≤ 0.1)

SB administration prevented the decrease in H3K9ac in the CGP group; however, the effect did not reach statistical significance ( p = 0.053 vs CGP + NaCl group, p = 0.45 vs VEH + NaCl group) and did not affect the VEH group ( p = 0.29 vs VEH + NaCl group; Fig. 11 ).

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