Specific targeting of PDGFRβ in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression.

Theranostics · 2020 · PMC6956815 · PMID 31938055

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showed a trendno p-value reported

B16 tumors, which comprise low PDGF-BB paracrine signaling, showed a trend towards decreased PDGFRβ+ pericyte coverage of tumor vessels after treatment with 1-NaPP1 as well as imatinib, whereas no change was observed on NG2+ pericyte coverage ( Figure S2 I-J ).

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