12-h clock regulation of genetic information flow by XBP1s.

Similar to the 1,573 commonly identified 12-h transcriptomes, 2,382 eigenvalue-specific XBP1s-dependent 12-h transcriptomes were also significantly enriched in CEDIF pathways ( Fig 3H and 3I ), many of which exhibited reduced amplitude in XBP1 LKO mice but did not reach statistical significance of FDR < 0.05 by the DODR analysis (such as Sec61a1 and Ddx55 ) ( S3N and S3O Fig ).

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