Context-Dependent Roles for SIRT2 and SIRT3 in Tumor Development Upon Calorie Restriction or High Fat Diet.

Front Oncol · 2019 · PMC6960403 · PMID 31970087

Europe PMC DOI

hedged sentence

0.0100

closest p · 0.2× alpha

0.0100

boldest claim

The sentences

did not reach statistical significancep = 0.01actually significant

Although there was a trend toward decreased survival in the Sirt2 −/− ; p53 +/− mice under HFD, they seemed to be partially protected as the decrease in tumor incidence did not reach statistical significance ( Sirt2 −/− ; p53 +/− : HFD vs. ctrl survival p = 0.01 / tumor incidence p = 0.1).

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