Following stimulation with PMA/ionomycin, NR4A1 and CD83 expression levels were significantly upregulated in total B-cells ( Figure 5 F,G left panels) and there was a strong trend for increased expression by total CD39 + B-cells ( Figure 5 F,G right panels), but levels of expression by MZ populations were less significantly affected ( Figure 5 F,G middle panels) presumably in relation to their already elevated expression levels ex vivo.
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