Improving the Efficiency of Respiratory Drug Delivery: A Review of Current Treatment Trends and Future Strategies for Asthma and Chronic Obstructive Pulmonary Disease.

Pulm Ther · 2017 · PMC6964260 · PMID 32026344

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a clear trendno p-value reported

There is a clear trend of increased hospitalizations, mortality, loss of productivity as well as overall poorer quality of life in nonadherent patients [ 26 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.