Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor.

PLoS One · 2020 · PMC6964819 · PMID 31945128

Europe PMC DOI

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failed to reach statistical significanceno p-value reported

IL-15, MCSF, MIG, and ITAC/CXCL11, among others) was higher based on data collected on the extracellular vesicle surface than the data collected in the soluble fraction of amniotic fluid, yet the difference failed to reach statistical significance.

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may be significantno p-value reported

While the relative amount of internal mediators is low, their biological effect may be significant as vesicles can deliver these mediators to the very vicinity of the target cells.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.