Extracellular Vesicles From Hepatocytes Are Therapeutic for Toxin-Mediated Fibrosis and Gene Expression in the Liver.

A similar trend but one that did not reach statistical significance occurred for triggering receptor expressed on myeloid cells 1 (TREM-1) ( Figure 3B ), which was recently reported to drive Kupffer cell activation, inflammation and fibrosis ( Nguyen-Lefebvre et al., 2018 ).

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