Preparation, evaluation and metabolites study in rats of novel amentoflavone-loaded TPGS/soluplus mixed nanomicelles.

Drug Deliv · 2020 · PMC6968485 · PMID 31913733

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a clear trendno p-value reported

As shown in Figure 6 , it could be seen that the cellular uptake of AMF and AMF-loaded TPGS/soluplus mixed micelles had a clear trend of increase over time.

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an increasing trendno p-value reported

At the same time, it can be seen that when AMF was at a lower concentration, the fatality rate of A549 cells was less than 0, which indicating that the low concentration of AMF had a small inhibitory effect on A549 cells, and the cells continued growing under conditions of sufficient nutrition, so the cell concentration showed an increasing trend, and the cell inhibition rate was less than 0. 3.6.

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