Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis.

Front Immunol · 2019 · PMC6970977 · PMID 31993059

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Quantification of CNS infiltrating CD4 + T cells ( Figure 6K ) showed a trend toward reduction of the numbers of CD4 + T cells in the brain of ICAM-1/-2 −/− mice suffering from either typical and atypical EAE.

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