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A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells.

Sci Rep · 2020 · PMC6971260 · PMID 31959800

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In the case of dCas9-VPR cells, TCF4 and POGZ protein levels both trended toward an increase, although the results did not reach statistical significance.

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