Horses with equine recurrent uveitis have an activated CD4+ T-cell phenotype that can be modulated by mesenchymal stem cells in vitro.

Equine recurrent uveitis horses have an activated CD4 + blood T‐cell phenotype CD4 + T‐cells from ERU horses expressed significantly higher levels of IFNγ ( P = .01, Figure 1 A) than control horses, and showed a trend toward expressing lower levels of IL‐10 ( P = .07, Figure 1 B), indicative of a shift toward a Th1 activation phenotype.

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