mRNA expression of Plb, Atp2a2 and Ryr2 trended to be decreased in PAB mice, however did not reach statistical significance. mRNA expression was not affected by the genotype (Fig. 7 b). βMhc/αMhc ratio was markedly higher in PAB than in sham mice.
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FHL-1 is not involved in pressure overload-induced maladaptive right ventricular remodeling and dysfunction.
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