Endoplasmic Reticulum Stress Pathway, the Unfolded Protein Response, Modulates Immune Function in the Tumor Microenvironment to Impact Tumor Progression and Therapeutic Response.

Int J Mol Sci · 2019 · PMC6981480 · PMID 31881743

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a clear trendno p-value reported

Although the intricacies of UPR signaling in cancer microenvironment have not yet been deciphered, there is a clear trend that optimal levels of UPR signaling confer immune protection and may assist in the progression of cancer.

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