In addition, NECA, regadenoson and LUF5835 were able to increase the inhibition of platelet function caused by the anti-thrombotic activity of P2Y 12 inhibitors (reduction of thrombus volume was up to 75% compared to P2Y 12 antagonist alone), although the changes did not reach statistical significance.
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Adenosine Receptor Agonists Exhibit Anti-Platelet Effects and the Potential to Overcome Resistance to P2Y<sub>12</sub> Receptor Antagonists.
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