Whole-Exome Sequencing of Matched Primary and Metastatic Papillary Thyroid Cancer.

Overall, no significant difference was observed in the mutation burden of subclonal mutations between primary and metastatic lesions ( p = 0.265, Mann–Whitney U test), although we note that a nominally significant difference was observed in 12/14 cases ( p = 0.039, Mann–Whitney U test).

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