50 In a similar study, a significant increase in total antioxidant capacity and elevated SOD activity in the PC12 clone, developed from a pheochromocytoma tumor of the rat adrenal medulla treated with quercetin was quite significant compared to control cells. 51 It has been demonstrated that the breviscapine flavonoids collection (derived from Chinese herb Erigeron breviscapus ) effectively neutralizes radiated free radicals and subsequently increases the total intracellular antioxidant capacity by attenuation of lipid peroxidation, thereby contributing to the cytoprotective role from ionizing radiation. 52 Ping et al evaluated the effects of amentoflavone radiation protection by measuring cell viability, apoptosis, and ROS levels after exposure to 8 Gy gamma rays from 60 Co in guinea pig pulmonary fibroblast cells.
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An Overview of the Cellular Mechanisms of Flavonoids Radioprotective Effects.
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