Experimental Traumatic Brain Injury Induces Chronic Glutamatergic Dysfunction in Amygdala Circuitry Known to Regulate Anxiety-Like Behavior.

Front Neurosci · 2019 · PMC6985437 · PMID 32038140

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

approached significancep = 0.053so close (0.05 < p ≤ 0.1)

Protein levels of mature BDNF were decreased by 43% (t 7 = 2.07; p < 0.05; d = 1.33; Figure 4H ) (BDNF precursor was not different; Figure 4G ) and GluR approached significance with a 20% decrease (t 7 = 1.854; p = 0.053; Figure 4I ).

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a trend toward significanceno p-value reported

No significant differences were measured between 7 DPI and 28 DPI for both OFT and glutamate neurotransmission, however, a trend toward significance was observed over time post-injury.

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