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Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.

J Exp Clin Cancer Res · 2020 · PMC6993409 · PMID 32000827

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showed a trendno p-value reported
Western blotting analysis of PKM2, HIF-1α and PPAR-γ also showed a trend towards decreased protein levels in the Sora + Sim group.

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