In the liver and skeletal muscle, the levels of all 16:0 PlsEtn species (except for 16:0/22:4) and the 16:0 plasmalogen pool showed a trend towards improvement following PPI-1040 treatment ( Fig. 5 A,B).
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Oral administration of a synthetic vinyl-ether plasmalogen normalizes open field activity in a mouse model of rhizomelic chondrodysplasia punctata.
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