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Increased Risk of Systemic Lupus Erythematosus in Patients With <i>Helicobacter pylori</i> Infection: A Nationwide Population-Based Cohort Study.

Front Med (Lausanne) · 2019 · PMC7000519 · PMID 32064263

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Additionally, our study found that patients aged >65 years with HP infection had a lower risk of SLE but did not reach statistical significance.

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a decreasing trendno p-value reported
By age–sex subgroup analysis ( Table 5 ), the highest aHR (12.74; 95% CI: 1.55–104.59) was observed in female patients <30 years old with HP infection, and a decreasing trend of SLE risk was observed in patients aged >65 years with HP infection.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.