Mastiha (Pistacia lentiscus) Improves Gut Microbiota Diversity, Hepatic Steatosis, and Disease Activity in a Biopsy-Confirmed Mouse Model of Advanced Non-Alcoholic Steatohepatitis and Fibrosis.

34 Due to the absence of targeted pharmacological therapy, there is an increasing trend in the evaluation of the effectiveness of natural products in combination with lifestyle dietary changes.

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Biochemical Profile Treatment with Mastiha led to a significant reduction in plasma ALT activity (Figure 1 d) and a nonsignificant trend toward lower plasma AST activity (Figure 1 e).

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There was no significant difference in body composition between mice with or without exposure to Chios mastic gum, though mice on Mastiha showed a trend to lower relative fat mass (Figure S1, Supporting Information). 3.2.

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