N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug.

Additionally, AS-1 slightly decreased the mean duration of events, but results did not reach statistical significance (Fig. 7 c; two-way ANOVA, pretreatment: F (1,32) = 5.58, p > 0.05; treatment: F (1,32) = 22.39, p < 0.01; pretreatment × treatment interaction: F (1,32) = 4.52, p > 0.05; n = 5–12/group).

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